教授
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查正宝
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姓 名:
查正宝
职 称:
教授
职 务:
所属系:
生物医学科学系
邮 箱:
zbzha@hfut.edu.cn
电 话:
 
个人学习工作简介
2015.01~至今,      合肥工业大学生物与医学工程学院,教授,黄山青年学者;
2013.11~2014.12      美国休斯顿卫理公会医院研究所,博士后研究员;
2009.11~2011.01      美国亚利桑那大学,访问学者;
2009.09~2013.07      哈尔滨工业大学,生物医学工程,工学博士;
2007.09~2009.07      哈尔滨工业大学,生物医学工程,工学硕士;
2003.09~2007.07      哈尔滨工业大学,  生物工程,  工学学士
主要研究领域与方向
1、多功能诊疗试剂的开发
2、分子影像学
3、重大疾病的早期即时诊断
代表性研究成果
       主要从事多功能癌症诊疗一体化药剂的开发,药物靶向传递和缓控释,生物材料表面修饰等方面的研究。目前在Advanced Materials,Scientific Reports,Biomaterials,Chemical Communications,Nanoscale,Applied Physics Letters等国际著名杂志上发表SCI期刊论文21篇(第一作者SCI论文11篇),会议论文5篇,已申请专利2项。
目前承担科研项目
黄山青年学者---科研启动基金
获奖情况
1、哈尔滨工业大学第十六届优秀博士论文奖;
2、获得2011年教育部“博士研究生学术新人奖”;
3、哈尔滨工业大学第二届“优秀学生李昌奖”
发表的论文、专利与著作(代表作)
1. Zhengbao Zha, Xiuli Yue, Qiushi Ren and Zhifei Dai. Uniform Polypyrrole Nanoparticles with High Photothermal Conversion Efficiency for Photothermal Ablation of Cancer cells. Advanced Materials, 2013, 25(5): 777-782. (SCI, IF: 15.409)
2. Zhengbao Zha, Celine Cohn, Zhifei Dai, Weiguo Qiu, Jinhong Zhang and Xiaoyi Wu. Nanofibrous Lipid Membranes Capable of Functionally Immobilizing Antibodies and Capturing Specific Cells. Advanced Materials, 2011, 23(30): 3435-3440. (SCI, IF: 15.409)
3. Zhengbao Zha, Jinrui Wang, Enze Qu, Shuhai Zhang, Yushen Jin, Shumin Wang and Zhifei Dai. Polypyrrole Hollow Microspheres as Echogenic Photothermal Agent for Ultrasound Imaging Guided Tumor Ablation. Scientific Reports, 2013, 3: 2360. (Nature Publishing Group, SCI, IF: 5.078 )
4. Zhengbao Zha, Jinrui Wang, Shuhai Zhang, Shumin Wang, Enze Qu, Youyi Zhang and Zhifei Dai. Engineering of perfluorooctylbromide polypyrrole nano-/microcapsules for simultaneous contrast enhanced ultrasound imaging and photothermal treatment of cancer. Biomaterials, 2014, 35(1): 287-293. (SCI, IF: 8.312)
5. Zhengbao Zha, Shuhai Zhang, Zijian Deng, Yanyan Li, Changhui Li and Zhifei Dai. Enzyme-Responsive Copper Sulphide Nanoparticles for Combined Photoacoustic Imaging, Tumor-Selective Chemotherapy and Photothermal Therapy. Chemical Communications, 2013, 49: 3455-3457. (SCI, IF: 6.718)
6. Zhengbao Zha, Shumin Wang, Shuhai Zhang, Enze Qu, Hengte Ke, Jinrui Wang and Zhifei Dai. Targeted Delivery of CuS Nanoparticles through Ultrasound Image-Guided Microbubble Destruction for Efficient Photothermal Therapy. Nanoscale, 2013, 5: 3216-3219. (SCI, IF: 6.739)
7. Zhengbao Zha, Zijian Deng, Yanyan Li, Changhui Li, Jinrui Wang, Shumin Wang, Enze Qu and Zhifei Dai. Biocompatible Polypyrrole Nanoparticles as a Novel Organic Photoacoustic Contrast Agent for Deep Tissue Imaging. Nanoscale, 2013, 5: 4462-4467. (SCI, IF: 6.739)
8. Zhengbao Zha, Linan Jiang, Zhifei Dai and Xiaoyi Wu. A Biomimetic Mechanism for Antibody Immobilization on Lipid Nanofibers for Cell Capture. Applied Physics Letters, 2012, 101(19): 193701. (SCI, IF: 3.515)
9. Zhengbao Zha, Siuling Leung, Zhifei Dai and Xiaoyi Wu. Centering of Organic-Inorganic Hybrid Liposomal Cerasomes in Electrospun Gelatin Nanofibers. Applied Physics Letters, 2012, 100(3): 033702. (SCI, IF: 3.515)
10. Zhengbao Zha, Weibing Teng, Valerie Markle, Zhifei Dai and Xiaoyi Wu. Fabrication of Gelation Nanofibrous Scaffolds Using Ethanol/Phosphate Buffer Saline as a Benign Solvent. Biopolymers, 2012, 97(12): 1026-1036. (SCI, IF: 2.288)
11. Zhengbao Zha, Yan Ma, Xiuli Yue, Meng Liu and Zhifei Dai. Self-Assembled Hemocompatible Coating on Poly (vinyl chloride) Surface. Applied Surface Science, 2009, 256(3): 805-814. (SCI, IF: 2.538)
其他情况
       欢迎具有生物学、化学、材料等相关背景的有志青年加入本研究小组。
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